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Appetite control by food odors and pheromones

Posted on April 8, 2013 by James Kohl.

Appetite control could be rewired, say researchers 5 April 2013

Excerpt: “Researchers looked in detail at the hypothalamus section of the brain, which is known to regulate sleep, energy expenditure, appetite, thirst and many other critical biological functions.”

Excerpt: “It was previously thought that nerve cells in the brain associated with appetite regulation were generated entirely during an embryo’s development in the womb and could not be altered.”

My comment: Experience-dependent nerve cell generation has been modeled throughout life and exemplified in many model organisms. This report exemplifies the neurogenic niche construction, which is required in my model of nutrient-dependent pheromone-controlled adaptive evolution. Article excerpt [subscription required] “…during postnatal and adult life, the hypothalamus regulates a diverse set of adaptable functions, ranging from thermoregulation and circadian rhythm to appetite/energy balance.” The hypothalamus also regulates the physiology of reproduction in mammals like us.

I have also detailed the fact that organism-level thermoregulation is adaptively evolved via ecological, social, and neurogenic niche construction, which is thermodynamically controlled intracellularly. This links microbes to man via the same molecular mechanisms of adaptive evolution that people seem unwilling to discuss if they favor a mutations-based theory of evolution. For comparison, there has never been any scientific support for a mutations-based theory of adaptive evolution.

This article and my works link more than just the molecular mechanisms of appetite control to adaptively evolved behavior. The link from nutrients and their metabolism to pheromones that control nutrient-dependent reproduction is also clearer and the common molecular mechanisms are thereby extended to sexual reproduction in mammals like us (sans mutations theory).

The biological facts have become so evident that no matter how thoroughly entrenched in mutations theory others have become, they will at some point need to begin to dig themselves out of their hole if they wish to participate in discussions that lead to scientific progress. We will then begin to see how much harm has been done by “mutations theory” and how much it has  retarded scientific progress.  But, there is no doubt we WILL see this.

Kohl, J.V. (2012) Human pheromones and food odors: epigenetic influences on the socioaffective nature of evolved behaviors. Socioaffective Neuroscience & Psychology, 2: 17338.

Kohl, J.V. (2013) Nutrient-dependent / Pheromone-controlled thermodynamics and thermoregulation

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James Kohl
Retired medical laboratory scientist

James Kohl




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