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Creation vs Evolution? Pre-existing genetic variation, not random mutation

Posted on April 11, 2012 by James Kohl.

Article link:

Stickleback genomes reveal path of evolution

“…evolution is accelerated by the use of pre-existing genetic variation, instead of waiting for new, random mutations to arise…”

Full text is free: Jones, F. C. et al. Nature. (2012).

My Comment to the Nature site:

The honeybee is an invertebrate model organism that exemplifies the vertebrate molecular mechanisms detailed here. As noted by the authors, these molecular mechanisms are common to microbial species, which indicates the requirement for their ubiquitous and consistent use across life’s evolutionary continuum.

In the honeybee, what the queen eats determines her pheromone production and everything else about the colony, including the neuroanatomy of the worker bee’s brains. From this perspective on molecular biology, the honeybee model tells us that nutrient chemicals calibrate receptor-mediated intracellular signaling and stochastic gene expression associated with the metabolism of nutrients to pheromones in all species from microbes to man. The pheromones standardize regulatory control of receptor-mediated intracellular signaling and stochastic gene expression required for speciation. Reciprocal bottom-up / top-down relationships among chemicals associated with the “odors” of food are directly responsible for the formation of an ecological niche, which is maintained by the “social odors” / the pheromones that establish the social niche.

Changes in nutrient chemicals result in changes in the ecological niche that change the social niche by partial suppression of reproduction in individuals that don’t “smell” right because they are malnourished (or in bacterial colonies where reproduction is suppressed by pheromones and quorum sensing). The ability to acquire sufficient nutrient chemicals is genetically predisposed but also depends on conspecifics and stressors in the social niche (e.g., dominance in mammals) that might prevent access to changing supplies of existing nutrients. Individuals with genetic predispositions that allow them to adapt to changes associated with available nutrients will reproduce in microbial species like bacteria, or pheromonally signal their reproductive fitness in yeasts or in the multicellular organisms of all other species. These nutritional and social stressors are associated with immune system dysfunction in primates as they are with nutritional deficits or excess in other species.

In species from yeasts to primates, this model allows incorporation of social science theories of individual selection, kin selection, and group selection where nutrition and food odors are as essential to individual survival as they are to the production of pheromones and species survival. In this context, olfaction and odor receptors provide a clear evolutionary trail that can be followed from unicellular organisms to insects to humans.



James Kohl
Retired medical laboratory scientist

James Kohl

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What is the vomeronasal organ (VNO)?

The vomeronasal organ (VNO) is a cone-shaped organ in the nasal cavity, which is believed to be one of the body's receptors of pheromones. More, specifically, the VNO, which is part of the accessory olfactory system in the nose, does not respond to normal scents, but may detect odorless, barely perceptible pheromones.

Other schools of thought believe that it is not the VNO but rather cells in our main olfactory system and their affects on hormones secreted by the hypothalamus that are responsible for the affects of pheromones.

Learn more about the science behind pheromones here.

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