Epistasis: Epigenetic effects of nutrient chemicals and their metabolism to pheromones

November 6, 2012 | James Kohl

The genetics of molecular evolution.  November 6th, 2012.

Excerpt: “The study of the factors determining the tempo and mode of molecular evolution continues to be at the forefront of evolutionary biology. Many studies have focused on the role of selection versus genetic drift in the fixation of amino-acid substitutions. Scientists are now certain that both, selection and genetic drift, contribute to a substantial fraction of all amino-acid substitutions in the course of evolution.”

My comment: Isn’t the balance of microRNA and messenger RNA responsible for the stochastic gene expression required for adaptive evolution via ecological, social, neurogenic, and socio-cognitive niche construction? If so, epistasis is achieved via the epigenetic effects of nutrient chemicals, which are balanced by the epigenetic effects of their metabolism to pheromones that control reproduction in species from microbes to man.

The likelihood that individuals eat to survive and that their pheromones control reproduction of their species is not a novel idea. But perhaps I’ve made it too complicated in my most recently published work. Should I have titled it: Epistasis, instead of Human pheromones and food odors: epigenetic influences on the socioaffective nature of evolved behaviors. Socioaffective Neuroscience & Psychology, 2: 17338.



James Vaughn Kohl

James Vaughn Kohl

James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones.