Pheromones and the reform of psychiatry’s diagnostic doctrine

May 19, 2013 | James Kohl

Excerpt: “The blog post made waves in the media and rattled some psychiatric clinicians and researchers. But Insel says that he has been talking about the issue since 2008. “The word was just still not out there,” he says. Insel says that he has increasingly received complaints from grant applicants who have tried to follow his guidance, only to be shot down by peer reviewers for eschewing DSM scripture.”

This is the message I received when I attempted to post to the topic thread: Psychiatry framework seeks to reform diagnostic doctrine. “You do not have permission to post on this thread”

I’ve been shot down by someone at Here is what I had hoped to convey.

Attempts to get the word out there (e.g., since 2008) have been hindered by those who seem to prefer their theories to explanations of biological facts. For example:

Kohl (2012) “The gene, cell, tissue, organ, organ-system pathway is a neuroscientifically established link between sensory input and behavior. Marts and Resnick (2007) stress the importance of this pathway in the context of a systems biology approach to pharmacogenomics. Naftolin (1981) stressed its importance to the understanding of sex differences. This pathway is sensitive to conditioning. Sensory input from an organism’s environment activates and reactivates the pathway and causes changes in hormone secretion that condition hormone-driven behavior.”

Kohl (2012) “The FDA Critical Path Initiative
Given the importance of understanding how food odors and nutrition epigenetically
influence individual survival in other mammals, it is not surprising that a reiteration of the ‘FDA Critical Path Initiative’ (Marts & Resnick, 2007) stresses the need to approach the development of human sexual behavior, which is required for our species survival and beneficial to human well-being, by using the same pathway that links food odors and pheromones to the behavior of honeybees and humans.”

Kohl (2012) “Integration of olfactory/pheromonal conditioning into clinical
psychology: The American Society of Addiction Medicine (ASAM) policy statement

The Public Policy Statement: Definition of Addiction (ASAM, 2011) represents a paradigm shift that may move the current practice of clinical psychology forward. It dictates the adoption and integration of neuroscientific principles that are required in order to understand differences between genetically predisposed brain disease, naturally occurring variations of behavioral development, and choice. These neuroscientific principles include focus on how sensory input influences behavior. The statement specifically mentions food and sex along with drugs and alcohol; each seems to chemically condition changes in hormones and in behavioral responses.”

Note: The excerpts above come from an open access publication that details a model of nutrient-dependent pheromone-controlled adaptive evolution, which helps to explain what goes wrong in mental and in physical disorders using current perspectives from molecular biology and neuroscience.


Kohl, J.V. (2012) Human pheromones and food odors: epigenetic influences on the socioaffective nature of evolved behaviors. Socioaffective Neuroscience & Psychology, 2: 17338.



James Vaughn Kohl

James Vaughn Kohl

James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones.