Random mutations: nothing adaptive in 3 billion years

Review article: Human cytochromes P450 in health and disease

Daniel W. Nebert, Kjell Wikvall, and Walter L. Miller

Phil. Trans. R. Soc. B February 19, 2013 368 20120431; doi:10.1098/rstb.2012.0431

Article excerpt (with my emphasis): “With the explosion of molecular biology in the 1980s, it became clear that P450 genes existed in virtually all species—from prokaryotes to rodents and humans [14], and alignment of deduced amino acid sequences led to the first proposal of a gene superfamily nomenclature system based on evolutionary divergence [15]. This evolutionary concept also implied that all CYP genes today arose from a single ancestor, which originated probably more than 3 billion years ago.

My comment: This is an open access article. Any advocate of adaptive evolution via random mutations can attempt to find evidence that I could not find by scanning it. Please tell someone when you find it, and if you don’t tell them why you think anyone would believe in such a ridiculous theory as a basis for adaptively evolved human behavior.

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Author: James Kohl

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