Sold on the human VNO?

May 21, 2010 | jim

Recent discoveries show that human pheromones are signals that are processed by cells in our main olfactory system. http://www.ncbi.nlm.nih.gov/pubmed/17917120

Accordingly, as they do in all other mammals, pheromones activate the hypothalamus in humans. http://www.ncbi.nlm.nih.gov/pubmed/19235878

Human pheromones cause behavior to change via their effects on hormones secreted by the hypothalamus. http://senseofsmell.org/papers/Human_Pheromones_Final%207-15-09.pdf

Though it is widely reported to exist, the adult human vomeronasal organ (VNO) is not functional. http://www.ncbi.nlm.nih.gov/pubmed/10531049; http://www.ncbi.nlm.nih.gov/pubmed/11369678; http://www.ncbi.nlm.nih.gov/pubmed/15470677

It contains few nerve cells and consists largely of epithelial cells, which means it has no sensory function. http://www.ncbi.nlm.nih.gov/pubmed/4068105

Most cells of the adult human VNO express the protein markers of skin cells, not nerve cells. No cells have synaptic contacts, and there is no evidence that any nerve connects with the human VNO. http://www.ncbi.nlm.nih.gov/pubmed/10944499; http://www.ncbi.nlm.nih.gov/pubmed/12107500

Finally, no cells express the protein that is the primary indicator of mature olfactory nerve cells. http://www.ncbi.nlm.nih.gov/pubmed/336785

If you think you’ve found scientific support for misleading claims about a functional human VNO, look further and see what other researchers say in the links to the articles above.

These next few links are to articles that focus on research that apparently is supported by a woman who claims to be the co-discoverer of human pheromones based on the acclamations of television.

http://www.ncbi.nlm.nih.gov/pubmed/9883309 comment on http://www.ncbi.nlm.nih.gov/pubmed/9494686. http://www.ncbi.nlm.nih.gov/pubmed/15327919 comment on http://www.ncbi.nlm.nih.gov/pubmed/11897264, and on http://www.ncbi.nlm.nih.gov/pubmed/9494686.

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James Vaughn Kohl

James Vaughn Kohl

James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones.