Sold on the human VNO?
May 21, 2010 | jim
Recent discoveries show that human pheromones are signals that are processed by cells in our main olfactory system. http://www.ncbi.nlm.nih.gov/pubmed/17917120
Accordingly, as they do in all other mammals, pheromones activate the hypothalamus in humans. http://www.ncbi.nlm.nih.gov/pubmed/19235878
Human pheromones cause behavior to change via their effects on hormones secreted by the hypothalamus. http://senseofsmell.org/papers/Human_Pheromones_Final%207-15-09.pdf
Though it is widely reported to exist, the adult human vomeronasal organ (VNO) is not functional. http://www.ncbi.nlm.nih.gov/pubmed/10531049; http://www.ncbi.nlm.nih.gov/pubmed/11369678; http://www.ncbi.nlm.nih.gov/pubmed/15470677
It contains few nerve cells and consists largely of epithelial cells, which means it has no sensory function. http://www.ncbi.nlm.nih.gov/pubmed/4068105
Most cells of the adult human VNO express the protein markers of skin cells, not nerve cells. No cells have synaptic contacts, and there is no evidence that any nerve connects with the human VNO. http://www.ncbi.nlm.nih.gov/pubmed/10944499; http://www.ncbi.nlm.nih.gov/pubmed/12107500
Finally, no cells express the protein that is the primary indicator of mature olfactory nerve cells. http://www.ncbi.nlm.nih.gov/pubmed/336785
If you think you’ve found scientific support for misleading claims about a functional human VNO, look further and see what other researchers say in the links to the articles above.
These next few links are to articles that focus on research that apparently is supported by a woman who claims to be the co-discoverer of human pheromones based on the acclamations of television.
http://www.ncbi.nlm.nih.gov/pubmed/9883309 comment on http://www.ncbi.nlm.nih.gov/pubmed/9494686. http://www.ncbi.nlm.nih.gov/pubmed/15327919 comment on http://www.ncbi.nlm.nih.gov/pubmed/11897264, and on http://www.ncbi.nlm.nih.gov/pubmed/9494686.