Data from the ENCODE project attest to the odds against any individual of any species surviving long enough to reproduce. The only way to beat those odds would be to allow nutrient chemicals to epigenetically effect intracellular signaling and stochastic gene expression
Has anyone else detailed the required bottom-up/top-down reciprocity of the adaptively evolved gene, cell, tissue, organ, organ system pathway, which is exemplified in the honeybee model organism I used to link the adaptive evolution of microbes to man?
Taken together, these two open-access articles from the supplement offer a concise and reasonably accurate overview of the receptor-mediated events that are required for adaptive evolution.
My idea is that nutrient chemical-dependent ecological niche construction and pheromone-dependent social niche construction contribute equally to the neurogenic niche construction that is responsible for adaptive evolution, development of the mammalian brain, and construction of our socio-cognitive niche.
As readers learn more about adaptive evolution, I hope they will return to Pheromones.com to learn what additional progress is being made in detailing how olfaction and odor receptors provide a clear evolutionary trail that can be followed from unicellular organisms to insects to humans.
Nutrient chemicals cause ecological niches to form that enable interactions among the conspecifics of social niches. Nutrition and pheromones are both required for epigenetic effects on development of a neurogenic niche in the honeybee brain and a hypothalamic neurogenic niche in the mammalian brain.
I’ve dismissed evolutionary theory that involves random mutations, and used the epigenetic effects of olfactory/pheromonal input on OR variants, which provide a clear evolutionary trail that can be followed from unicellular organisms to insects to humans,