Vitamin A causes mutations (or not)

March 21, 2014 | James Kohl

Vitamin A’s Influence on Immunity

Exposure to vitamin A in the womb influences immune system development and lifelong ability to fight infections, a mouse study shows.

By Ashley P. Taylor | March 19, 2014

Excerpt:  “The present study is the first to suggest that this development can be altered by maternal behavior.”

My comment: There’s a model for that!  It links nutrient stress and social stress to mammalian immune system function and nutrient-dependent pheromone-controlled ecological adaptations via conserved molecular mechanisms in species from microbes to man.

Nutrient-dependent/pheromone-controlled adaptive evolution: a model

Excerpt: “Embryos with retinoic acid receptor mutations had a smaller percentage of inducer cells than controls.”

My comment: That suggests the mutations do not contribute to adaptive evolution. Does anyone who is not a population geneticist think that mutation-driven evolution is biologically plausible?

Like all other experimental evidence, I think the results from this study show that ecological variation enables ecological adaptations. For contrast, only evidence from population genetics suggests that mutation-initiated natural selection is possible — and that evidence is not experimental evidence. Therefore, the idea that vitamin A causes mutations may seem like pseudoscientific nonsense to some molecular biologists, but not to those who believe in mutation-driven evolution.

Comments

comments

James Vaughn Kohl

James Vaughn Kohl

James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones.